Control Charts are widely used to identify changes in the production process, and when it comes to identifying small changes in the process, non-Shewhart Control Charts such as exponential weighted moving average (EWMA) and generalized weighted moving average (GWMA) are better alternatives to Control Charts than Shewhart 𝑋 Control Chart. In this context, Nonparametric Control Charts are used when the distribution of quality characteristic of the process is unknown, in which the Sign Control Chart is one of the most popular Nonparametric Control Charts. In this paper, for the first time, a generalized weighted moving average sign Control Chart using a ranked set sampling (RSS) design is introduced. The performance of the proposed Control Chart is evaluated using simulated data according to the average run length evaluation criterion, and simulation studies showed that the GWMA sign Control Chart under the RSS design is better at detecting small process changes than the EWMA sign Control Chart under the RSS design. The performance of the proposed Control Chart has been evaluated using simulated data according to the average execution length evaluation criteria in Julia software, and the simulation studies show that due to changes in the regulatory parameter α, the 𝐺𝑊𝑀𝐴𝑆𝑅𝑆𝑆 + Control Chart is more sensitive than the 𝐸𝑊𝑀𝐴𝑆𝑅𝑆𝑆 + Control Chart in discovering small process changes, also the 𝐺𝑊𝑀𝐴𝑆𝑅𝑆𝑆 + Control Chart is more sensitive than the 𝐺𝑊𝑀𝐴𝑆𝑆𝑅𝑆 + and 𝐷𝐺𝑊𝑀𝐴𝑆𝑆𝑅𝑆 + Control Charts are more efficient and sensitive in identifying small process changes, which shows the advantage of RSS scheme over SRS scheme. In addition, it was proved that increasing k and the number of cycles and large values of q decrease 𝐴𝑅𝐿1 and increase the power of the Control Chart in identifying process changes.